Chronic cerebrospinal venous insufficiency in Ménière disease.
Phlebology. 2015 May;30(4):274-9. doi: 10.1177/0268355514526871. Epub 2014 Mar 4.
Di Berardino F1, Alpini DC2, Bavera PM3, Cecconi P4, Farabola M4, Mattei V2, Ambrosetti U5, Cesarani A5.
The aim of this study was to focus on patients suffering from cochleo-vestibular disorder with and without Ménière disease (MD) in order to verify whether chronic cerebrospinal drainage abnormalities could play a role in the etiopathogenesis of endolymphatic hydrops.
Fifty-two volunteers were enrolled and subdivided into two groups: 24 definite MD and 28 not-MD. Both magnetic resonance venography imaging with contrast-enhanced imaging of the venous cerebrospinal system (MRV) and venous echo-color Doppler (ECD) were performed.
MRV showed abnormalities in 83% of MD and 57% of not-MD subjects (p < 0.001). Asymmetrical cervical venous flow, assessed by MRV, was confirmed by ECD in 62.5% of MD but in only 21.5% of not-MD subjects (p<0.001).
Chronic cerebrospinal venous insufficiency might be the anatomical background, which provides a predisposing factor for the development of endolymphatic hydrops in MD patients.
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